4.6 Fertility, pregnancy and lactation Pregnancy There is inadequate proof of the protection of codeine in human pregnancy, but there's epidemiological evidence for the protection of paracetamol. Equally substances are applied for many years without apparent unwell consequences and animal scientific studies have not shown any hazard.
與其它鴉片類藥物一樣，可待因的其中一個潛在的嚴重不良反應是壓抑呼吸，通常與服用過量有關，可引致死亡。
You are aware of you are a sluggish or intermediate metaboliser of the enzyme known as CYP2D6, mainly because a special dose might be applicable to you personally.
3). All kids gained doses of codeine which were inside the suitable dose range; on the other hand there was proof that these little ones have been possibly ultra-swift or in depth metabolisers of their ability to metabolise codeine to morphine.
Seldom, expanding the dose of the medication might make you additional sensitive to suffering. If this transpires, you have to talk to your prescriber about your cure.
Administration to nursing women is not really proposed as codeine might be secreted in breast milk and will bring about respiratory depression in the infant.
Generic remedies have exactly the same active ingredient as the initial branded medication and operate the identical way but may differ in shape or measurement. Most Accord drugs are generic prescription drugs.
If you can get any Unintended effects, discuss with your medical professional, pharmacist or nurse. This involves any achievable Unwanted website side effects not listed during the bundle leaflet.
Codeine should not be used for pain reduction in small children and adolescents immediately after elimination in their tonsils or adenoids because of Obstructive Slumber Apnoea Syndrome.
Regardless of the Unwanted effects and risks pointed out, codeine remains a often prescribed medication in both standard exercise and clinic medicine.
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Most Individuals who have taken codeine will mention a standard side-outcome of constipation. This happens because the codeine metabolite cuts down the flexibility with the bowel check her to move contents alongside its duration.
Liquor and opioids The concomitant usage of alcohol and opioids enhances the possibility of sedation, respiratory depression, coma and Dying due to additive CNS depressant outcome. Concomitant use with alcohol is just not recommended (see segment four.four).
o You have got taken it according to the Directions specified from the prescriber and in the information provided with the medicine and